研究成果

原著論文  Google Scholar  ResearcherID
  1. Shirai K. Matsuda F. Nakabayashi R. Okamoto M. Tanaka M. Fujimoto A. Shimizu M. Shinozaki K. Seki M. Saito K. Hanada K. (2017) A highly specific genome-wide association study integrated with transcriptome data reveals the contribution of copy number variations to specialized metabolites in Arabidopsis thaliana accessions. Molecular Biology and Evolution https://doi.org/10.1093/molbev/msx234 New!
  2. Sano N. Kim JS. Onda Y. Nomura T. Mochida K. Okamoto M. Seo M. (2017) RNA-Seq using bulked recombinant inbred line populations uncovers the importance of brassinosteroid for seed longevity after priming treatments. Scientific Reports 10.1038/s41598-017-08116-5  New!
  3. Takeuchi J*. Okamoto M*, Mega R. Kanno Y. Ohnishi T. Seo M. Todoroki Y.  (2016) Abscinazole-E3M, a practical inhibitor of abscisic acid 8’-hydroxylase for improving drought tolerance. Scientific Reports 10.1038/srep37060
  4. Yan D. Easwaran V. Chau V. Okamoto M. Ierullo M. Kimura M. Endo A. Yano R. Pasha A. Gong Y. Bi YM. Provart N. Guttman D. Krapp A. Rothstein SJ. Nambara E. (2016) NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nature Communications 7:13179
  5. Okamoto M. Matsui M. Tanaka M. Morosawa T. Ishida J. Iida K. Mochizuki Y. Toyoda T. Seki M. (2016) Sm-like protein-mediated RNA metabolism is required for heat stress tolerance in Arabidopsis. Frontiers in Plant Science fpls.2016.01079
  6. Yamashita Y. Ota M. Inoue Y. Hasebe Y. Okamoto M. Inukai T. Masuta C. Sakihama Y. Hasidoko Y. Kojima M. Sakakibara H. Inage Y. Takahashi K. Yoshihara T. Matsuura H. (2016) Chemical Promotion of Endogenous Amount of ABA in Arabidopsis thaliana by a Natural Product, Theobroxide. Plant & Cell Physiology 57: 986–999
  7. Takeuchi J. Ohnishi T. Okamoto M. Todoroki Y. (2015) The selectivity of 6-nor-ABA and 7′-nor-ABA for abscisic acid receptor subtypes. Bioorganic & Medicinal Chemistry Letters 25 3507–3510
  8. Takeuchi J. Ohnishi T. Okamoto M. Todoroki Y. (2015) Conformationally restricted 3′-modified ABA analogs for controlling ABA receptors. Organic & Biomolecular Chemistry 13, 4278-4288
  9. Takeuchi J.* Okamoto M.* Akiyama T. Muto T. Yamaji S. Sue M. Seo M. Kanno Y. Kamo T. Endo A. Nambara E. Hirai N. Ohnishi T. Cutler SR. Todoroki Y. (2014) Designed abscisic acid analogues as antagonists of PYL-PP2C receptor interactions. Nature Chemical Biology 10:477-482
  10. Okamoto M. Higuchi-Takeuchi M. Shimizu M. Shinozaki K. Hanada K. (2014) Substantial expression of novel small open reading frames in Oryza sativa. Plant Signaling & Behavior e27848-1-3
  11. Okamoto M. Peterson FC. Defries A. Park SY. Endo A. Nambara E. Volkman BF. Cutler SR. (2013) Activation of dimeric ABA receptor elicits guard cell closure, ABA-regulated gene expression and drought tolerance. Proc. Natl. Acad. Sci. USA 110: 12132-7
  12. Hanada K.* Higuchi-Takeuchi M.* Okamoto M. Yoshizumi T. Shimizu M. Nakaminami K. Nishi R. Ohashi C. Iida K. Tanaka M. Horii Y. Kawashima M. Matsui K. Toyoda T. Shinozaki K. Seki M. Matsui M. (2013) Small coding genes associated with morphogenesis are hidden in plant genomes. Proc. Natl. Acad. Sci. USA 110: 2395-400
  13. Kawaguchi S. Iida K. Harada E. Hanada K. Matsui A. Okamoto M. Shinozaki K. Seki M. Toyoda T. (2012) Positional correlation analysis improves reconstruction of full-length transcripts and alternative isoforms from noisy array signals or short reads. Bioinformatics 28: 929-937
  14. Endo A.* Tatematsu K.* Hanada K.* Duermeyer L. Okamoto M. Yonekura-Sakakibara K. Saito K. Toyoda T. Kawakami N. Kamiya Y. Seki M. Nambara E. (2012) Tissue-specific transcriptome analysis reveals cell wall metabolism, flavonol biosynthesis, and defense responses are activated in the endosperm of germinating Arabidopsis thaliana seeds.  Plant & Cell Physiology 53: 16-27
  15. Hanada K. Hase T. Toyoda T. Shinozaki K. Okamoto M. (2011) Origin and evolution of genes related to ABA metabolisms and signaling pathways. Journal of Plant Research 124:455-465
  16. Okamoto M. Kushiro T. Jikumaru Y. Abrams SR. Kamiya Y. Seki M. Nambara E. (2011) ABA 9’-hydroxylation is catalyzed by CYP707A in Arabidopsis. Phytochemistry 72:717-722
  17. Okamoto M. & Seki M. (2011) Expression pattern and 5’-terminal structure of antisense transcripts. Plant Signaling & Behavior 6:691-693
  18. Iida K.* Kawaguchi S.* Kobayashi N. Yoshida Y. Ishii M. Harada E. Hanada K. Matsui A. Okamoto M. Ishida J. Tanaka M. Morosawa T. Seki M. Todyoda T. (2011) ARTADE2DB: Improved Statistical Inferences for Arabidopsis Gene Functions and Structure Predictions by Dynamic-Structure-Based Dynamic Expression (DSDE) Analyses. Plant & Cell Physiology 52:254-64
  19. Okamoto M. Tatematsu K. Matsui A. Morosawa T. Ishida J. Tanaka M. Endo TA. Mochizuki Y. Toyoda T. Kamiya Y. Shinozaki K. Nambara E. Seki M. (2010) Genome-wide analysis of endogenous abscisic acid-mediated transcription in dry and imbibed seeds of Arabidopsis using tiling arrays. Plant Journal 62:39-51
  20. Ikegami K. Okamoto M. Seo M. and Koshiba T. (2009) Activation of abscisic acid biosynthesis in the leaves of Arabidopsis thaliana in response to water deficit. Journal of Plant Research 122:235-243
  21. Okamoto M. Tanaka Y. Abrams SR. Kamiya Y. Seki M. Nambara E. (2009) High humidity induces abscisic acid 8’-hydroxylase in stomata and vasculature to regulate local and systemic abscisic acid responses in Arabidopsis. Plant Physiology 149: 825-834
  22. Matsui A. Ishida J. Morosawa T. Mochizuki Y. Kaminuma E. Endo TA. Okamoto M. Nambara E. Nakajima M. Kawashima M. Kim JM. Satou M. Kobayashi N. Toyoda T. Shinozaki K. and Seki M. (2008) Arabidopsis Transcriptome Analysis under Drought, Cold, High-Salinity and ABA Treatment Conditions using a Tiling Array. Plant & Cell Physiology 49:1135–1149
  23. Endo A. Sawada Y. Takahashi H. Okamoto M. Ikegami K. Koiwai H. Seo M. Toyomasu T. Mitsuhashi W. Shinozaki K. Nakazono M. Kamiya Y. Koshiba T. and Nambara E. (2008) Drought induction of Arabidopsis 9-cis-epoxycatotenoid dioxygenase 3 occurs in vascular parenchyma cells. Plant Physiology 147:1984–1993
  24. Toh S. Imamura A. Watanabe A. Nakabayashi K. Okamoto M. Jikumaru Y. Hanada A. Aso Y. Ishiyama K. Tamura N. Iuchi S. Kobayashi M. Yamaguchi S. Kamiya Y. Nambara E. and Kawakami N. (2008) High temperature-induced abscisic acid biosynthesis and its role in the inhibition of gibberellin action in Arabidopsis seeds. Plant Physiology 146:1368–1385
  25. Melhorn V. Matsumi K. Koiwai H. Ikegami K. Okamoto M. Nambara E. Bittnerb F. and Koshiba T. (2008) Transient expression of AtNCED3 and AAO3 genes in guard cells causes the stomatal closure inVicia faba L. Journal of Plant Research 121:125-131
  26. Saika H. Okamoto M. Miyoshi K. Kushiro T. Shinoda S. Jikumaru Y. Fujimoto M. Arikawa T. Takahashi H. Ando M. Arimura S. Miyao A. Hirochika H. Kamiya Y. Tsutsumi N. Nambara E. Nakazono M. (2007) Ethylene promotes submergence-induced expression of OsABA8ox1, a gene that encodes ABA 8´-hydroxylase in rice. Plant & Cell Physiology 48:287-298
  27. Lin P. Hwang S. Endo A. Okamoto M. Koshiba T. Cheng W. (2007) Ectopic Expression of ABA2/GIN1 in Arabidopsis Promotes Seed Dormancy and Stress Tolerance. Plant Physiology 143:745-758
  28. Saito S. * Okamoto M. * Shinoda S. Kushiro T. Koshiba T. Kamiya Y. Hirai N. Todoroki Y. Sakata K. Nambara E. Mizutani M. (2006) A Plant Growth Retardant Uniconazole Is a Potent Inhibitor of ABA Catabolism in Arabidopsis. Bioscience, Biotechnology, and Biochemistry 70:1731-1739
  29. Okamoto M. Kuwahara A. Seo M. Kushiro T. Asami T. Hirai N. Kamiya Y. Koshiba T. Nambara E. (2006) CYP707A1 and CYP707A2, which encode ABA 8’-hydroxylases, are indispensable for a proper control of seed dormancy and germination in Arabidopsis. Plant Physiology 141:97-107
  30. Seo M. Hanada A. Kuwahara A. Endo A. Okamoto M. Yamauchi Y. North H. Marion-Poll A. Tai-ping S. Koshiba T. Kamiya Y. Yamaguchi S. Nambara E. (2006) Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism. Plant Journal 48:345-366
  31. Umezawa T. Okamoto M. Kushiro T. Nambara E. Oono Y. Seki M. Kobayashi M. Koshiba T. Kamiya Y. Shinozaki K. (2006) CYP707A3, a major ABA 8’-hydroxylase involved in dehydration and rehydration response in Arabidopsis thaliana. Plant Journal 46:171-182
  32. Lefebvre V. North H. Frey A. Sotta B. Seo M. Okamoto M. Nambara E. Marion-Poll A. (2006) Functional analysis of Arabidopsis NCED6 and NCED9 genes indicates that ABA synthesised in the endosperm is involved in the induction of seed dormancy. Plant Journal 45: 309-319
  33. Nakabayashi K. Okamoto M. Koshiba T. Kamiya Y. Nambara E. (2005) Genome-wide profiling of stored mRNA in Arabidopsis thaliana seed germination: epigenetic and genetic regulation of transcription in seed. Plant Journal 41: 697-709
  34. Gazzarrini S. Tsuchiya Y. Lumba S. OkamotoM. McCourt P. (2004) The transcription factor FUSCA3 controls developmental timing in Arabidopsis through the hormones gibberellin and abscisic acid. Developmental Cell 7: 373-385
  35. Kushiro T.* Okamoto M.* Nakabayashi K. Yamagishi K. Kitamura S. Asami T. Hirai N. Koshiba T. Kamiya Y. Nambara E. (2004) The Arabidopsis Cytochrome P450 CYP707A Family Encodes ABA 8’-Hydroxylases: Key Enzymes in ABA Catabolism. EMBO Journal 23: 1647-1656.

(*Co-first authors)

総説等
  1. Okamoto M. Cutler SR. Chemical control of ABA receptors to enable plant protection against water stress (in press) New!
  2. 岡本昌憲 (2017) 「アブシジン酸受容体と受容体に作用する化合物について」 植調 Vol.50, No.12: 366-371 New!
  3. 岡本昌憲 (2016) 「アブシジン酸の代謝と受容に関する化学遺伝学的研究」 植物の生長調節 51 (1): 16-23
  4. 岡本昌憲、妻鹿良亮 (2015) 「植物の乾燥ストレス応答を制御するアブシジン酸の働きとその応用」 極限環境生物学会誌 12: 78-88  
  5. Yan D. Tatematsu K. Nakabayashi K. Endo A. Okamoto M. Nambara E. (2015) A comparison of transcriptomes between germinating seeds and growing axillary buds of Arabidopsis, Advances in Plant Dormancy Springerp223-234
  6. Endo A, Okamoto M, Koshiba T. (2014) ABA biosynthetic and catabolic pathways. Abscisic acid: Metabolism, Transport and Signaling, Springer Science21-45.
  7. 竹内純、岡本昌憲、轟泰司 (2014) アブシジン酸受容体のアンタゴニストの合理的な創出 「ライフサイエンス新着レビュー」
  8. Matsui A, Ishida J, Morosawa T, Okamoto M, Kim JM, Kurihara Y, Kawashima M, Tanaka M, To TK, Nakaminami K, Kaminuma E, Endo TA, Mochizuki Y, Kawaguchi S, Kobayashi N, Shinozaki K, Toyoda T, Seki M. (2010) Arabidopsis tiling array analysis to identify the stress-responsive genes. Method in Molecular Biology The Humana Press Inc. 639:141-55.
  9. Nambara E. Okamoto M. Tatematsu K. Yano R. Seo M. Kamiya Y. (2010) Abscisic acid and the control of seed dormancy and germination. Seed Science Research Cambridge University Press20:55-67
  10. Seki M. Okamoto M. Matsui A. Kim MJ. Kurihara Y. Kim-To T. and Shinozaki K. (2009) “Microarray analysis for studying plant abiotic stress responses”, Molecular Techniques in Crop Improvement, 2nd edition Springer publisherp333-35
  11. Okamoto M. Hanada A. Kamiya Y. Yamaguchi S. Nambara E. (2009)Chapter 9 Measurements of abscisic acid and gibberellins by gas chromatography/massspectrometryMethod in Molecular BiologyThe Humana Press Inc.495: 53-60
  12. 久城哲夫、岡本昌憲 (2009)ABA 8′位水酸化酵素による種子の発芽調節」種子発芽の生態学、生理学、分子生物学 (種生物学会刊行本)  279-286
  13. 南原英司、岡本昌憲、久城哲夫 (2004) ABA不活性化酵素CYP707A遺伝子の同定と機能解析 ブレインテクノニュース 104:26-29.
  14. 南原英司、岡本昌憲 (2004)「新版 植物ホルモンのシグナル伝達」第4章アブシジン酸;3.アブシジン酸とジベレリンのクロストーク 「植物細胞 工学シリーズ20号レビュー集」(秀潤社) 125-132.
特許およびその他
  1. 米国特許登録 : Sean Cutler、岡本昌憲 (2016) 「Synthetic Compounds for Vegetative ABA Responses」 US9345245
  2. 国内特許出願 : 花田耕介、樋口美栄子、吉積毅、中南健太郎、岡本昌憲、関原明、 松井南 (2012) 「植物の形態形成および/または環境ストレス耐性に関与するポリペプチド」
  3. 国内特許出願 : 南原英司、神谷勇治、久城哲夫、岡本昌憲 (2003) 「アブシジン酸不活性化に関与する遺伝子」